Image created by Dr. Michael J. Miller
bioMérieux, a biotechnology company specializing in in vitro diagnostics, launched GENE-UP TYPER SLM, a new real-time PCR solution supporting rapid root cause analysis by discriminating Salmonella in food industry environments.
The new assay specifically targets Salmonella enterica subspecies enterica, the subspecies most frequently isolated in human salmonellosis cases and in food-related incidents, said bioMérieux.
GENE-UP TYPER, launched early 2025 with the introduction of a test dedicated to Listeria monocytogenes, is a real-time PCR solution for rapid strain characterization of microorganisms, for use on bioMérieux's GENE-UP system.
Following pathogen detection during routine testing and isolation, DNA is extracted and amplified with the corresponding GENE-UP TYPER assay. The analytical result generated by the GENE-UP instrument is then uploaded to bioMérieux's AUGMENTED-DX web portal.
Powered by machine learning, GENE-UP TYPER combines advanced algorithms with years of expertise embedded in a comprehensive genomic database, said bioMérieux. It assigns a unique address identifying the strain and groups identical strains into “clusters.” The web application then progressively builds a historical view of the strain clusters detected within the factory, allowing to trace back the source of contamination for improved control of the production process, said the company.
“bioMérieux is continuing to drive innovation in cutting-edge science and technology, supporting food manufacturers as they navigate a rapidly shifting environment,” said Yasha Mitrotti, executive vice president, industrial applications, bioMérieux. “Following the successful launch of our Listeria assay last year, the introduction of GENE-UP TYPER for Salmonella is a natural continuation of our mission, bringing an innovative solution capable of rapidly supporting root cause analysis through genomics and data. This will help the industry reduce foodborne illness, ultimately enhancing consumer safety.”
The patented solution was developed over years of research, with contributions from Mérieux NutriSciences, a long-term partner of bioMérieux and a subsidiary of Institut Mérieux.
Mérieux NutriSciences will retain co-exclusive rights to perform testing in key geographies for the outsourced testing services channel, ensuring the solution is available to all food and beverage processors, whether they operate an internal laboratory or outsource pathogen testing, said bioMérieux.
The GENE-UP TYPER SLM test is now available worldwide for food manufacturers.